Page 16 - TRAMES-BP®
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Activation Syndrom linked with
Antidepressants
Activation syndrome (AS) = cluster of symptoms
listed by the US FAD as possible suicidality
precursor during antidepressant treatment.
AS Rate = 52.2% of BP-II/BP-NOS vs 13.5% of
MDD, (p<0.01).
Factors linked with AS (Univariate analysis):
BP-II/BP-NOS diagnosis
Cyclothymic temperament
Early age at onset of first MDE
Psychiatric comorbidities
Depressive mixed state (DMX)
Takeshima & Oka, J Affect Disord. 2013 Oct;151(1):196-202.
Antidepressants
Activation syndrome (AS) = cluster of symptoms
listed by the US FAD as possible suicidality
precursor during antidepressant treatment.
AS Rate = 52.2% of BP-II/BP-NOS vs 13.5% of
MDD, (p<0.01).
Factors linked with AS (Univariate analysis):
BP-II/BP-NOS diagnosis
Cyclothymic temperament
Early age at onset of first MDE
Psychiatric comorbidities
Depressive mixed state (DMX)
Takeshima & Oka, J Affect Disord. 2013 Oct;151(1):196-202.
