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Specificity of Mixed Depressions versus



Pure Depressions in Bipolar Disorder






• Early onset




• Suicide risk



• More exposure to antidepressants




• Psychotic features




• Chronic course (more time in illness)




• Recurrent depression



• Rapid cycling




• Mood switching




Goldberg et al, 2009; Valenti et al, 2011, Azorin et al, 2012.
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