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Depression threshold according to MADRS-6
in defining “Mixed Mania”
Specificity Sensitivity
(% of less score (% of Higher score
In Pure Mania) In MM-II)
MADRS-6 items
10 99,5% 47,4%
9 99,1% 52,0%
8 97,7% 60,1%
7 96,6% 67,7%
6 94,2% 79,8%
MM-II= Mania with at least 2 depressive symptoms
Hantouche et al, JAD 2006 (“EPIMAN II Mille” survey)
