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Assessment of co-existing Depression in Acute Mania
List of Depressive Symptoms MADRS
Depressed Mood Apparent Sadness
Loss of Interest Expressed Sadness
Hypersomnia Inner Tension*
Psychomotor Retardation Sleep reduction *
Fatigue Appetite reduction*
Indignity / Guilt Feelings Concentration Difficulties*
Despair Feelings Lassitude
Thoughts of Death / Suicide Inability to feel
Lability Pessimistic Thoughts
Irritability Suicide Thoughts
* Possible contamination by Mania
Hantouche et al, JAD 2006 (“EPIMAN II Mille” survey)