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Assessment of co-existing Depression in Acute Mania






List of Depressive Symptoms MADRS




Depressed Mood Apparent Sadness


Loss of Interest Expressed Sadness


Hypersomnia Inner Tension*


Psychomotor Retardation Sleep reduction *


Fatigue Appetite reduction*


Indignity / Guilt Feelings Concentration Difficulties*


Despair Feelings Lassitude


Thoughts of Death / Suicide Inability to feel


Lability Pessimistic Thoughts


Irritability Suicide Thoughts



* Possible contamination by Mania

Hantouche et al, JAD 2006 (“EPIMAN II Mille” survey)
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