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Les options thérapeutiques actuelles de la
dépression bipolaire
• Quetiapina ++
• Haloperidol et
clorpromazina++ • Olanzapina ++
Quetiapina ++ A
• Tous les
antipsychotiques • Ziprasidona ++
atypiques, sauf (FDA + EMEA)
clozapine • Aripiprazol ++
• Clozapina +
Olanzapina + fluoxetina
++ A (FDA) • Rsperidona +
manie aiguë Maintenance
dépression aiguë
++ = At least 1 fully powered, randomized, placebo-controlled, double-blind, Controlled parallel-group, positive monotherapy trial;+ = At least 1 positive randomized controlled trial or
small placebo-controlled, double-blind, parallel-group trial; N = No data. - = evidence of lack of efficacy.
Vieta & Rosa, World J Biol Psychiatry, 2007:8:4-11.
