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Lamotrigine dans la dépression bipolaire
Add-on study
MADRS Response* rates
to lithium
P = 0.005 P=0.21
P=0.89 P = 0.03
P=0.36 P=0.42
**
Calabrese JR, et al, 2008 *Response = 50% improvement over baseline
Geddes J et al, 2009 Pooled Relative Risk of Response: 1.22 CI 1.06-1.41. P = 0.005
** Van der Loos M et al, 2009
