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Asenapine improved depressive




symptoms in manic/mixed patients







Patients with baseline MADRS ≥20









LS mean (±SE) change from
baseline MADRS total score

Asenapine (n=45)


Placebo (n=33)


Olanzapine (n=54)








**


**





Szegedi et al. BMC Psychiatry 2011;11:101


24 Post-hoc analysis; **p≤0.01 vs placebo; p=0.02 vs olanzapine
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