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Past Response to Antidepressants
(Bridge Study)
(%) BPD+ BPD-
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Hypomanic switches with AD 33.4 18.0
Mood lability with AD 62.8 35.5
Irritability with AD 55.0 29.7
Resistance to AD treatment 33.3 21.3
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All comparisons p<.0001
BPD = Borderline Pers. Disorder
Perugi G. SOPSIMeeting 2013