Page 42 - Elie HANTOUCHE
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Endogenous versus Exogenous Cyclicity in BP
Disorder: Role of Affective Temperaments
(Koukopoulos et al, JAD, 2006)
(Hypo)Mania Hypomania
Depression
AD
Basic Stable - Instable -
temperament Hyperthymic Complex Cyclothymic
Sequence MDI DMI
Cyclicity Exogenous Endogenous
Episodic, Instability,
Evolution
free intervals tendency to rapid cycling
Worsening effect of
Prophylactic effect of
Reactivity to lithium via attenuating antidepressants (formation
of rapid cycling; chronic
treatment hyperthymia mixed state; mood
switching)
Disorder: Role of Affective Temperaments
(Koukopoulos et al, JAD, 2006)
(Hypo)Mania Hypomania
Depression
AD
Basic Stable - Instable -
temperament Hyperthymic Complex Cyclothymic
Sequence MDI DMI
Cyclicity Exogenous Endogenous
Episodic, Instability,
Evolution
free intervals tendency to rapid cycling
Worsening effect of
Prophylactic effect of
Reactivity to lithium via attenuating antidepressants (formation
of rapid cycling; chronic
treatment hyperthymia mixed state; mood
switching)
