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Affective temperaments and
antidepressant response
• Lifetime history of AD response of 90 BP and 88
MDD
• Significant relationship between depressive and
anxious affective temperaments and no
antidepressant response.
• In BP: cyclothymic temperament (p<0.01) and
hyperthymic temperament (p<0.05) were
associated with antidepressant-associated mania.
• In MDD: Hyperthymic temperament was
associated with complete antidepressant
responses
De Aguiar Ferreira A et al. J Affect Disord. 2014 Feb;155:138-41
